Publications

HIV-1 diversity and prevalence differ between urban and rural areas in the Mbeya region of Tanzania

Arroyo, Miguel Aa; Hoelscher, Michaelb; Sateren, Warrena; Samky, Eleuterc; Maboko, Leonardd; Hoffmann, Olivere; Kijak, Gustavof; Robb, Merlinf; Birx, Deborah La; McCutchan, Francine Ef

Inter-subtype recombinant HIV-1, and the co-infections that generate them, are a key feature of the HIV-1 pandemic. Recombination following dual infection with genetically distinct subtypes or strains of HIV-1 is now recognized with increasing frequency in the global epidemic [1–4; Piyasirisilp S, et al. 2005, unpubl. results] HIV-1 risk behaviors and community prevalence often correlate with the frequency of HIV-1 dual infection [Herbinger KH, et al. 2005, unpubl. results]..........

Published at:  2005-09-23

Single-Dose Azithromycin versus Penicillin G Benzathine for the Treatment of Early Syphilis

Gabriele Riedner, M.D., Ph.D., Mary Rusizoka, Dipl.Med., Jim Todd, M.Sc., Leonard Maboko, M.D., Michael Hoelscher, M.D., Donan Mmbando, M.D., Eleuter Samky, M.D., Eligius Lyamuya, Ph.D., David Mabey, M.D., Ph.D., Heiner Grosskurth, M.D., Ph.D., and Richard Hayes, D.Sc.

Pilot studies suggest that a single, 2-g oral dose of azithromycin may be an alternative to a 2.4-MU intramuscular dose of penicillin G benzathine in the prevention and treatment of syphilis. We evaluated the efficacy of treatment with azithromycin in a developing country.

Published at:  2005-09-22

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